UNITY Fetal Risk™ Screen

Fetal risk for recessive conditions via cell-free DNA

UNITY Fetal Risk Screen leverages cell-free DNA to provide direct insights to the fetus, translating to ~3x increase in detection of affected pregnancies compared to traditional carrier screening.

Proven to maximize detection of affected pregnancies in a general obstetric population

The risk identified with UNITY Fetal Risk Screen is strongly correlated with the likelihood of an affected pregnancy

100% correlation of highest risk cases

All cases identified as a 9 in 10 risk were confirmed to have an affected child via neonatal outcomes

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Provide reassurance to 99% of patients

  • Detect more affected pregnancies than traditional carrier screening in a real life scenario
  • Does not require a male partner sample so is not limited by factors such as misattributed paternity (10%)14 or lack of partner follow up (58%)

42,000+

study cohort

cases collected from 811 unique practices across 45 US states 17.9% reflexed to sgNIPT

96.0%

key result

accurately detect affected pregnancies

Detect ~3x more affected pregnancies with UNITY Fetal Risk compared to traditional carrier screening

First-of-a-kind testing.
Backed by clinical data.

Maximize Detection. Minimize Risk.

This study builds upon earlier findings to confirm that carrier testing with reflex to sgNIPT is highly accurate for general population screening. Given this high accuracy and an NPV of 99.8%, this workflow should be considered as an option for most of the general pregnant population.

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42,000+

study cohort

cases collected from 811 unique practices across 45 US states 17.9% reflexed to sgNIPT

96.0%

key result

accurately detect affected pregnancies

528

neonatal outcomes obtained

at least 75 outcomes per condition

99.8%

negative predictive value (NPV)

trust in a negative result

Traditional Carrier Screen

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Less than 1% screen high risk

With earlier insights, diagnostic testing including Chorionic Villus Sampling, can be considered

Know More. Know Early. Timely treatment leads to optimal outcomes. Provide peace of mind for 99% of pregnancies.

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UNITY Fetal Risk™ Screen

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Frequently Asked Questions

UNITY Complete takes advantage of a pregnancy's DNA (circulating cell-free DNA, ccfDNA) floating in the maternal bloodstream to assess for genetic changes. Some of these genetic changes are extremely small - like changes to single genes that can cause recessive conditions. Some of these genetic changes involve the presence of an entire extra chromosome (aneuploidies).

Our specialized QCT technology enables us to be able to count the genetic information we see from both mom and baby in a blood sample, and determine if there are differences that could indicate a baby has a higher chance of being affected with one of these conditions.

UNITY Complete offers multiple genetic insights from a single maternal blood sample. The results you receive will depend on which tests your healthcare provider orders. UNITY Aneuploidy NIPT screens pregnancies for chromosome conditions caused by extra or missing chromosomes including trisomy 21, trisomy 18, trisomy 13, and monosomy X. This part of the test can also tell you the predicted sex of the baby and if there is a different number of sex chromosomes (XXX, XXY, XYY).

Depending on your clinical picture, your doctor may also order UNITY Fetal RhD NIPT for moms who have a RhD- blood type or UNITY Fetal Antigen NIPT for moms who are alloimmunized to certain antigens.

UNITY Fetal Risk Screen determines if a pregnant person is a carrier for cystic fibrosis, spinal muscular atrophy, sickle cell disease, alpha-thalassemia, or beta-thalassemia. If you're found to be a carrier for one of these conditions, the fetal DNA will be screened to determine if there is a high-chance or a low-chance for a pregnancy to be affected with a condition.

In some cases, like twin pregnancies or those achieved with an egg donor, we are not able to perform a fetal risk assessment.In some cases, your provider may also order carrier screening for fragile X syndrome. If you are a carrier for this, our assay cannot determine if the baby has fragile X syndrome or not. Additional testing would be recommended.

We accept ALL insurances, including Medicaid. UNITY Complete screens for recommended genetic conditions and are a covered benefit by most insurances, including Medicaid. Since each insurance plan is different, we will contact you with a text message or phone call about your out-of-pocket costs. We also offer financial assistance programs that are quick and easy. We believe every pregnant patient has the right to choose UNITY Complete without worrying about a surprise bill. If you have any questions or concerns with costs, please email us at support@unityscreen.com or call us at 650-460-2551

UNITY Complete is ordered by your healthcare provider. If you decide you want UNITY Complete, please call us at 650-460-2551 or email us at support@unityscreen.com and we can get your provider the information they need to get started.

The type and timing of results from your UNITY Complete tests will depend on what your provider orders. Our team of genetic counselors is always happy to review your specific results if you have further questions.

Possible results with UNITY Aneuploidy NIPT typically fall into low-risk fetus or high-risk fetus results.

A Low Risk Fetus Results means that the chance your pregnancy is affected with the screened conditions is significantly reduced, but not eliminated.
Note: this result does not guarantee a healthy child and does not eliminate the possibility of other chromosome abnormalities, birth defects, or other genetic conditions.

A High-Risk Fetus Result means the chance your pregnancy is affected with a specific condition is increased. Confirmatory testing via chorionic villus sampling, amniocentesis, or postnatal evaluation is strongly recommended.

UNITY Fetal Risk Screen provides maternal carrier screening results (reported as a positive carrier or negative carrier). If a pregnant person is found to be a carrier, fetal testing will automatically be performed. Possible sgNIPT fetal results can fall into decreased/low-risk categories or increased/high-risk categories.

UNITY Complete takes advantage of a pregnancy's DNA (circulating cell-free DNA, ccfDNA) floating in the maternal bloodstream to assess for genetic changes. Some of these genetic changes are extremely small - like changes to single genes that can cause recessive conditions. Some of these genetic changes involve the presence of an entire extra chromosome (aneuploidies).

Our specialized QCT technology enables us to be able to count the genetic information we see from both mom and baby in a blood sample, and determine if there are differences that could indicate a baby has a higher chance of being affected with one of these conditions.

UNITY Complete offers multiple genetic insights from a single maternal blood sample. The results you receive will depend on which tests your healthcare provider orders. UNITY Aneuploidy NIPT screens pregnancies for chromosome conditions caused by extra or missing chromosomes including trisomy 21, trisomy 18, trisomy 13, and monosomy X. This part of the test can also tell you the predicted sex of the baby and if there is a different number of sex chromosomes (XXX, XXY, XYY).

Depending on your clinical picture, your doctor may also order UNITY Fetal RhD NIPT for moms who have a RhD- blood type or UNITY Fetal Antigen NIPT for moms who are alloimmunized to certain antigens.

UNITY Fetal Risk Screen determines if a pregnant person is a carrier for cystic fibrosis, spinal muscular atrophy, sickle cell disease, alpha-thalassemia, or beta-thalassemia. If you're found to be a carrier for one of these conditions, the fetal DNA will be screened to determine if there is a high-chance or a low-chance for a pregnancy to be affected with a condition.

In some cases, like twin pregnancies or those achieved with an egg donor, we are not able to perform a fetal risk assessment.In some cases, your provider may also order carrier screening for fragile X syndrome. If you are a carrier for this, our assay cannot determine if the baby has fragile X syndrome or not. Additional testing would be recommended.

We accept ALL insurances, including Medicaid. UNITY Complete screens for recommended genetic conditions and are a covered benefit by most insurances, including Medicaid. Since each insurance plan is different, we will contact you with a text message or phone call about your out-of-pocket costs. We also offer financial assistance programs that are quick and easy. We believe every pregnant patient has the right to choose UNITY Complete without worrying about a surprise bill. If you have any questions or concerns with costs, please email us at support@unityscreen.com or call us at 650-460-2551

UNITY Complete is ordered by your healthcare provider. If you decide you want UNITY Complete, please call us at 650-460-2551 or email us at support@unityscreen.com and we can get your provider the information they need to get started.

The type and timing of results from your UNITY Complete tests will depend on what your provider orders. Our team of genetic counselors is always happy to review your specific results if you have further questions.

Possible results with UNITY Aneuploidy NIPT typically fall into low-risk fetus or high-risk fetus results.

A Low Risk Fetus Results means that the chance your pregnancy is affected with the screened conditions is significantly reduced, but not eliminated.
Note: this result does not guarantee a healthy child and does not eliminate the possibility of other chromosome abnormalities, birth defects, or other genetic conditions.

A High-Risk Fetus Result means the chance your pregnancy is affected with a specific condition is increased. Confirmatory testing via chorionic villus sampling, amniocentesis, or postnatal evaluation is strongly recommended.

UNITY Fetal Risk Screen provides maternal carrier screening results (reported as a positive carrier or negative carrier). If a pregnant person is found to be a carrier, fetal testing will automatically be performed. Possible sgNIPT fetal results can fall into decreased/low-risk categories or increased/high-risk categories.

UNITY Complete takes advantage of a pregnancy's DNA (circulating cell-free DNA, ccfDNA) floating in the maternal bloodstream to assess for genetic changes. Some of these genetic changes are extremely small - like changes to single genes that can cause recessive conditions. Some of these genetic changes involve the presence of an entire extra chromosome (aneuploidies).

Our specialized QCT technology enables us to be able to count the genetic information we see from both mom and baby in a blood sample, and determine if there are differences that could indicate a baby has a higher chance of being affected with one of these conditions.

UNITY Complete offers multiple genetic insights from a single maternal blood sample. The results you receive will depend on which tests your healthcare provider orders.

UNITY Aneuploidy NIPT screens pregnancies for chromosome conditions caused by extra or missing chromosomes including trisomy 21, trisomy 18, trisomy 13, monosomy X, XXX, XXY, and XYY. UNITY Aneuploidy NIPT can also tell you the baby's gender. For twin pregnancies, you will also learn if your twins are identical or fraternal.

Depending on your clinical picture, your doctor may also order UNITY Fetal RhD NIPT for moms who have a RhD- blood type, UNITY Fetal Antigen NIPT for moms who are alloimmunized to certain antigens, and 22q11.2 microdeletion analysis.

UNITY Fetal Risk Screen determines if a pregnant person is a carrier for cystic fibrosis, spinal muscular atrophy, sickle cell disease, alpha-thalassemia, or beta-thalassemia. If you're found to be a carrier for one of these conditions, the fetal DNA will be screened to determine if there is a high-chance or a low-chance for a pregnancy to be affected with a condition. In some cases, like twin pregnancies or those achieved with an egg donor, we are not able to perform a fetal risk assessment.

Your provider may also order carrier screening for fragile X syndrome. If the mom is determined to be a carrier for this, our assay can perform cell-free DNA analysis to determine if the fetus is a male- this would put the fetus at higher risk to develop Fragile X Syndrome.

We believe every pregnant patient has the right to choose UNITY Complete.

We accept ALL insurances, including Medicaid, and are in-network with the majority of insurance plans across the United States. We recognize that every patient's insurance and financial situation is unique. We have a dedicated patient services team to support patient needs, including payment plans or financial assistance for those who qualify. If you have any questions or concerns with costs, please email us at support@unityscreen.com or call us at 650-460-2551.

UNITY Complete is ordered by your healthcare provider. If you decide you want UNITY Complete, please call us at 650-460-2551 or email us at support@unityscreen.com and we can get your provider the information they need to get started.


Possible results with UNITY Aneuploidy NIPT typically fall into low-risk fetus or high-risk fetus results.

A Low Risk Fetus result means that the chance your pregnancy is affected with the screened conditions is significantly reduced, but not eliminated.

A High-Risk Fetus result means there is an increased chance for your pregnancy to be affected with a specific condition. Confirmatory testing via chorionic villus sampling,  amniocentesis, or postnatal evaluation is recommended.

Note: this result does not guarantee a healthy child and does not eliminate the possibility of other chromosome abnormalities, birth defects, or other genetic conditions.

UNITY Fetal Risk Screen provides maternal carrier screening results (reported as a positive carrier or negative carrier). If a pregnant person is found to be a carrier, fetal testing will automatically be performed via cell-free DNA analysis. Possible results from the fetal testing can fall into decreased/low-risk categories or increased/high-risk categories.