Overview:

While amniocentesis is the gold standard, many patients cannot, or choose not to, pursue invasive diagnostic testing^1-3. Unity Confirm is the first-and-only non-invasive confirmation test for high-risk Unity Aneuploidy Screen results* that uses whole genome sequencing of intact circulating fetal cells. Join Dr. Ramu Perni and fellow maternal-fetal medicine specialists for an in-depth clinical discussion on what this means for your practice.

What you'll learn:

• How Unity Confirm can expand access to critical insights for patients facing barriers to invasive testing
• Where Unity Confirm fits in the prenatal care pathway
• How Fetal Cell Capture™ technology isolates intact circulating fetal cells — delivering rapid CVS-like insights** — from a maternal blood draw
• The growing body of clinical evidence behind Unity Confirm and what the data means for your patients

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^{1Okoror, Collins Ejakhianghe Maximilian, and Suruchi Arora. “Prenatal diagnosis after high chance non-invasive prenatal testing for trisomies 21, 18 and 13, chorionic villus sampling or amniocentesis?–Experience at a district general hospital in the United Kingdom.”European Journal of Obstetrics & Gynecology and Reproductive Biology: X 19 (2023): 100211. 2Mokhtar, Rifat, et al. “Comparing noninvasive prenatal testing with invasive testing for the detection of trisomy 21.” Cureus 14.11 (2022). 3Chetty, Shilpa, Matthew J. Garabedian,and Mary E. Norton. “Uptake of noninvasive prenatal testing (NIPT) in women following positive aneuploidy screening.” Prenatal Diagnosis 33.6 (2013): 542-546.}

^{*Unity Confirm is not available for high-risk monosomy X pregnancies, twin or higher multiple pregnancies, vanishing twins, gestational carriers or egg donors, or for pregnancies >15 weeks 6 days gestation. Only available in the US.}

^{**Unity Confirm and rapid CVS both analyze fetal-derived trophoblast cells. Unity Confirm isolates individual cells via whole genome sequencing, which is performed on each cell separately, whereas rapid CVS is often performed via FISH. While rapid CVS may analyze more cells, WGS generates more data per cell. In both rapid CVS and fetal cell capture, mosaicism cannot be excluded. No medical decisions should be made based on Unity Confirm alone. Clinical correlation is necessary.}